Product Name: Preventol O Extra Preservative
EPA Registration Number: 39967-11
Manufacturer: Bayer Corp
Product Signal Word: DANGER, indicating that the final formulated product
which is a solution-ready-to-use is considered highly toxic prior to any
use dilution steps which may occur on the label.
99.9000% o-Phenylphenol (CAS# 90-43-7)
Classified as irritating to eyes and skin and has weak if any
sensitizing potential. Aqueous solution of 5.0% was found to be irritating
to skin of humans.
Rat and mouse oral LD50 values 2500-3000 mg/kg and 1000-2000 mg/kg
respectively with toxic signs reported as narcosis, tremors, ataxia and
hypothermia and haemorrhages in the lungs, liver, stomach, intestine and
heart. Following a single oral application, it is considered to be of low
toxicity. (J. Appl. Toxicol. 18, 261-270 1998)
If released into the atmosphere, gas phase o-Phenylphenol is
expected to degrade rapidly (estimated half-life of 13hr), Acclimated
microbes can biodegrade levels of o-phenylphenol which may occur in soils,
water and effluent. In a spill situation, o-phenylphenol is likely to be
toxic to local microbial populations. It has a low to moderate potential
to leach in most soil systems. (Hazardous Substance Database).
Information obtained from the Hazardous Substances Database
on sodium phenylphenate (the sodium salt of o-phenylphenol). List
environmental fate data referred to o-phenylphenol:
If released to air, a vapor pressure of 0.002 mm Hg at 25 deg C indicates
o-phenylphenol will exist solely as a vapor in the ambient atmosphere.
Vapor-phase o-phenylphenol will be degraded in the atmosphere by reaction
with photochemically-produced hydroxyl radicals; the half-life for this
reaction in air is estimated to be 14 hrs. o-Phenylphenol absorbs light in
the environmental UV spectrum and may undergo direct photolysis. If
released to soil, o-phenylphenol is expected to be immobile based upon an
estimated Koc of 10,000. Volatilization from moist soil surfaces is
expected to be an important fate process based upon a Henry's Law constant
of 4.3X10-5 atm-cu m/mole. o-Phenylphenol is not expected to volatilize
from dry soil surfaces based upon its vapor pressure. Biodegradation is
expected to occur based on the results of the Japanese MITI test where
o-phenylphenol reached 47-86% of its theoretical BOD in 2 weeks. If
released into water, o-phenylphenol is expected to adsorb to sediment and
suspended solids in water based upon the estimated Koc. Biodegradation in
water is expected based on a 50% reduction of o-phenylphenol concentration
within 1 week in river water from Midland, MI. Volatilization from water
surfaces may occur based upon this compound's Henry's Law constant.
Health Effects Data from the J. Appl. Toxicol. 18, 261-270
Irritating to skin and may cause serious eye damage.
Weak, if any sensitization properties.
May not be very toxic following single acute inhalatory exposure but
considered harmful following oral exposure.
Oral rat LD50 value of 1000-1700 mg/kg and Oral mouse LD50 value of